LYLES, KENNETH W.,COLON-EMERIC, CATHLEEN S.,OCONNOR, CHRISTOPHER M.,ABRAHAM, DENNIS,NILSSON, KENT,ROCKMAN, HOWARD,RUSSELL, GRAHAM
申请号:
CA2856030
公开号:
CA2856030A1
申请日:
2012.11.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention provides for methods and compositions for treating, reducing and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, prodrug thereof, functional analogue or a pharmaceutically effective salt thereof in an amount sufficient to increase activity of at least one kinase in heart tissue of the subject.