Oral Pharmaceutical Compositions Comprising Imatinib Mesylate

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专利权人:

发明人:

PRADEEP SHIVAKUMAR,KRISHNAMURTHY TOPPALADODDI,SANJAY UMACHIGI,BADRINATH ALAMPALLI,AKSHAYKANT CHATURVEDI

申请号：

US14901079

公开号：

US20160143850A1

申请日:

2014.06.25

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The invention relates to a granulate composition comprising 90-99.95% w/w of Imatinib mesylate, 0.05-0.2% w/w of binder and 0-8% w/w of disintegrant, wherein the granulate composition is prepared using binder in isopropyl alcohol solvent.The invention also relates to pharmaceutical compositions comprising Imatinib mesylate, with high polymorphic stability and processes for preparation thereof.Said granulate composition comprising 90-99.95% w/w of Imatinib mesylate and their pharmaceutical compositions derived may be useful in the treatment of cancer.

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