QUART BARRY,ROSENBAUM DAVID,Quart Barry,Rosenbaum David
申请号:
SI200731188
公开号:
SI2241318T1
申请日:
2007.04.30
申请国别(地区):
SI
年份:
2013
代理人:
摘要:
The present invention provides methods for treating constipation-predominant irritable bowel syndrome comprising administering to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat constipation-predominant irritable bowel syndrome (c-IBS). Treatment of c-IBS includes the treatment of the constipation component of c-IBS as well as the pain and abdominal discomfort associated with c-IBS. In one embodiment, the polymeric proanthocyanidin compound is crofelemer. The present invention in an alternative embodiment also provides methods for treating alternating constipation-predominant/diarrhea-predominant irritable bowel syndrome.