ARKENAU, ELISABETH,BARTHOLOMAEUS, JOHANNES,KUGELMANN, HEINRICH
申请号:
EP05757777.7
公开号:
EP1765298B1
申请日:
2005.06.29
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention relates to a method for producing a solid dosage form, which is safeguarded against abuse, contains at least one active ingredient that has an abuse potential, and contains a synthetic and/or natural polymer with a breaking resistance of at least 500 N. The invention is characterized in that a corresponding mixture is processed by melt extrusion with the aid of a planetary gear extruder.