Elisabeth Arkenau-Maric;Johannes Bartholomäus;Heinrich Kugelmann
发明人:
Elisabeth Arkenau-Maric,Johannes Bartholomäus,Heinrich Kugelmann
申请号:
US12140496
公开号:
US08323889B2
申请日:
2008.06.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a process for the production of an abuse-proofed solid dosage form containing at least one active ingredient with potential for abuse and a synthetic or natural polymer with a breaking strength of =500 N, characterized in that a corresponding mixture is processed by melt extrusion with the assistance of a planetary-gear extruder.