The present invention relates to selected bacterial strains belonging to the genus Bifidobacterium for use in the treatment of hypercholesterolaemia. In particular the present invention relates to a food composition or supplement product or medical device or pharmaceutical composition comprising said bacterial strains in association with sterols or phytosterols and/or stanols or phytostanols and/or glucomannan and/or konjac gum and/or prebiotic fibres and/or fermented red rice and/or betaglucans from oats oat bran barley barley bran and/or aloe arborescens gel in lyophilized form.