TAO, Ming,WENG, Lingkai,FRIETZE, William,MELONI, David J.,PAN, Yongchun,ZHOU, Jiacheng
申请号：
CR20190351
公开号：
CR20190351A
申请日:
2014.11.07
申请国别(地区):
CR
年份:
2019
代理人:
摘要：
La presente solicitud se refiere a procesos e intermedios para elaborar 4- (2- (aminosulfonil) amino etil amino) -N- (3-bromo-4-fluorofenil) -N -hidroxi-1 2 5-oxadiazol-3-carboximidamida queLa presente solicitud se refiere a procesos e intermedios para elaborar 4-({2-[(aminosulfonil)amino]etil}amino)-N-(3-bromo-4-fluorofenil)-N'-hidroxi-1,2,5-oxadiazol-3-carboximidamida, que es un inhibidor de indolamina 2,3-dioxigenasa útil en el tratamiento del cáncer y otros trastornos.The present application is directed to processes and intermediates for making 4-({2-[(aminosulfonyl)amino]ethyl}amino)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide, which is an inhibitor of indoleamine 2,3-dioxygenase, useful in the treatment of cancer and other disorders.
