TAO, Ming,FRIETZE, William,ZHOU, Jiacheng,MELONI, David J.,PAN, Yongchun,WENG, Lingkai
申请号:
CR20160252
公开号:
CR20160252A
申请日:
2014.11.07
申请国别(地区):
CR
年份:
2016
代理人:
摘要:
This application relates to processes and Intermediates for preparing 4 - ({2 - [(aminosulfonil) amino] ethyl] amino) - N - (3 - bromo - 4-fluorophenyl) - n '- hydroxy - 3 - carboximidamida 1,2,5 - Oxadiazoles, which is an inhibitor of indolamina 2,3-dioxygenase useful in the treatment of Cancer and other Disorders.La presente solicitud se refiere a procesos e intermedios para elaborar 4-({2-[(aminosulfonil)amino]etil}amino)-N-(3-bromo-4-fluorofenil)-N'-hidroxi-1,2,5-oxadiazol-3-carboximidamida, que es un inhibidor de indolamina 2,3-dioxigenasa útil en el tratamiento del cáncer y otros trastornos.