The formula compound (1) has the use as an FGF inhibitor and is helpful in the treatment of a disease in which it is desirable to inhibit FGF anions, such as cancer. 1. Claim 1: a formula compound (1) with the characteristics of Z being ch or N； ges-c (o) NR ° 8309； R1 8310；-C (O) OR-C (ch832323) = Noh or a set of formulas (2), where a is a phenyl ring or 5-12 member heterocyclic ring, R1 is h, tar c8332183318327；cycloquilo C83238C83318327；Cycloquilo c833238s-833183278a - rent c833218s-833183278a,Alcoxi C832188331832727；C83217c83318327c asphaltamino hidroxi hidroxialquilo CLet c83218c833183277 let - the lessor of c83218831277；b. Phenyl alcoxi c8321c83318327a；-NHC (O) -R-R -C (O) -R-SO 832220-R1 8308O-E-R8310A；h. R2 is h, halogen or c832183；B is a 5-12 member carbon ring or heterocyclic ring； R3 ° is h, halogen, alkyl c8332183318327832783；b) The stage of coating with carbonated glass fiber；R8308es h, halogen, hydrocarbyl c83318327u oxo； r8309es H-C (o) r8311811；-SO83228R831222，-C (o) - d-r8313 or optional 5-6 member heterocyclic ring； r8310 is optional 5-6 member heterocyclic ring； r8311 is c833218331838383；Alquenilo C8331832721；cycloquilo C83238C83318327；Alcoxi C832188331832727；Alcoxi C832188331832727；1. C83321833183277 lessor,Carboxil-Acquilo C8321C83318327A，alcoxi C carbonil-alquilo CLet c83218c833183277 let - the lessor of c83218831277；-Nh-r1 ° 830404 or nh-x1-r1；R831222 is lease No. c833218331832727,Alquenilo C8322833183277A，cycloquilo C83238C83318327；1.Hidroxi-Acquilo C83217C83318327E，-8312； 8313；-NH-X2-R830404，e. The results show that r8313 is phenyl, or 5-6 members are selectively replaced； r183044 is c8332183833183838383278c；R2 and R2 are c83218c831832727 rents；R1: alcox c833221353183277o amino； R1 ° 83088e: Aquilo c8321c833183277o；R83099,R8310,R18311,R831222 and r8313son, independent h, lease c83218831278o c832238318327；e. R 2830404 is phenyl, or 5-6 members of heterocyclic ring can be replaced optionally； E is c83218c833183727e；D is link or tenant c8332183
