Piperidylpyrimidine derivatives as modulators of protein kinase inhibitors and of vascular endothelial growth factor receptor 2

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专利权人:

发明人:

Julie A. Wurster,Thomas C. Malone,Clarence Eugene Hull, III,Sandhya Rao,Rong Yang,Richard Yee

申请号：

US14511326

公开号：

US09296747B1

申请日:

2014.10.10

申请国别(地区):

US

年份:

2016

代理人:

摘要：

This invention is directed to a compound of Formula Ior a pharmaceutically acceptable salt thereof, wherein X, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. The compounds of Formula I are useful as protein kinase (PK) inhibitors and can be used to treat such diseases as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, metabolic diseases inflammatory disorders and neurodegenerative disorders.

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