new melamine (5.4 - d] pirimidin derivatives as inverse agonists of the adenosine a2a receptor

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专利权人:

UNIVERSITÀ DEGLI STUDI DI FERRARA;UNIVERSITÀ DEGLI STUDI DI FIRENZE

发明人:

VARANO, Flavia,COLOTTA, Vittoria,CATARZI, Daniela,VARANI, Katia,BOREA, Pier Andrea,VINCENZI, Fabrizio,VARANO FLAVIA,COLOTTA VITTORIA,CATARZI DANIELA,VARANI KATIA,BOREA PIER ANDREA,VINCENZI FABRIZIO

申请号：

IT201600070952

公开号：

IT201600070952A1

申请日:

2016.07.07

申请国别(地区):

IT

年份:

2018

代理人:

摘要：

The present invention refers to novel thiazolo[5,4-d]pyrimidine derivatives that are inverse agonists of the adenosine A2A receptor, to a process for their preparation, to the pharmaceutical compositions containing them and to their use in the medical field, in particular in the therapeutic treatment of diseases or disorders associated to an activity of the adenosine A2A receptor, and more in particular in the therapeutic treatment of neurological diseases, of pain, of cancer, and of dermal fibrosis and scarring.

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中国工程科技知识中心

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