Jin Cheul Kim,Jae Ho Kim,Eun Jin Yoon,Yong Il Kim,Jae Hyun Park,Jong Soo Woo
申请号:
US14358853
公开号:
US20140314844A1
申请日:
2012.11.16
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to an oral complex formulation comprising omega-3 fatty acid or its derivatives encapsulated in a hard or soft capsule containing sorbitol and sorbitan, as well as an HMG-CoA reductase inhibitor. The formulation of the present invention comprising omega-3 fatty acid encapsulated with sorbitol and sorbitan provides better prevention related materials from being formed, leading to improved long-term storage stability. The oral complex formulation of the present invention also can raise the serum HDL-cholesterol level, while reducing both LDL-cholesterol and TG levels. The oral complex formulation of the present invention is useful for treatment of hyperlipidemia.