KIM, JIN CHEUL,KIM, JAE HO,YOON, EUN JIN,KIM, YONG IL,PARK, JAE HYUN,WOO, JONG SOO
申请号:
EP12850234
公开号:
EP2780002A4
申请日:
2012.11.16
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to an oral complex formulation comprising omega-3 fatty acid or its derivatives encapsulated in a hard or soft capsule containing sorbitol and sorbitan, as well as an HMG-CoA reductase inhibitor. The formulation of the present invention comprising omega-3 fatty acid encapsulated with sorbitol and sorbitan provides better prevention related materials from being formed, leading to improved long-term storage stability. The oral complex formulation of the present invention also can raise the serum HDL-cholesterol level, while reducing both LDL-cholesterol and TG levels. The oral complex formulation of the present invention is useful for treatment of hyperlipidemia.