An individualized imaging method, comprising the following steps: scanning an imaging subject mould conducting calibration, rectification and optimization on the imaging system according to the information obtained after mould imaging: scanning the imaging subject with the calibrated, rectified and optimized imaging system optimizing information obtained by scanning the imaging subject and the mould thereof to obtain higher quality imaging results and data analysis result and applying the higher quality imaging results and data analysis results to optimize the mould for use in the next imaging. The individualized imaging method fully utilizes a priori knowledge, establishes a mould for an individual and uses the image data information of the mould to conduct calibration, rectification and optimization on the imaging system, and optimizes the image data information of the imaging subject, and further optimizes the mould. By repeating the above steps, the present invention can obtain higher quality imaging results and data analysis results.