Shih-Hsiung Wu,Chung-Yi Wu,I-Ming Lee,Feng-Ling Yang
申请号:
US16442334
公开号:
US20200179503A1
申请日:
2019.06.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein is a glycocojugate vaccine conferring protection against a Gram negative pathogen infection, a method of manufacturing the glycoconjugate vaccine, and use of the glycocojugate vaccine for treating bacterial infection. The glycocojugate vaccine of the present disclosure has the structure of formula (I),wherein, L is a maleimide-type linker, which is connected to the carrier protein via a maleimide bond formed therebetween; and n and m are respectively an integral or a non-integral number between 2 and 20.