this invention relates to compositions comprising the protein and the pilin of haemophilus influenzae. more specifically, the present application relates to fusion proteins comprising the immunogenic protein and compositions and vaccines containing these compositions), immunogenic, and their therapeutic uses.Cette invention concerne des compositions comprenant la protéine e et la piline a d'haemophilus influenzae. Plus particulièrement, la présente demande concerne des protéines de fusion et des compositions immunogènes comprenant la protéine e et pila, des vaccins contenant ces compositions immunogènes et leurs utilisations thérapeutiques.