PROBLEM TO BE SOLVED: To address the necessity for a technique to improve perforation performances of a calcified total occlusion lesion in particular, where a lesioned part is currently treated by using an outer coil of a large wire size for the outside of a core wire tip end of a guide wire or a coil composed of a two-layer structure providing an inner coil inside the outer coil.SOLUTION: A tip side of a core wire tip end of a guide wire is inserted into an outer coil. A minimum buckling stress ratio of the core wire of a minimum buckling stress in the core wire tip end relative to that of a large-diameter part of a hand-side core wire rear end is enhanced several-fold to several ten-fold of the well-known patent literature so as to significantly improve perforation properties at a calcified total occlusion lesion in particular.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2018,JPO&INPIT【課題】ガイドワイヤの芯線先端部の外側に、線径の大きな外側コイルを用い、又は、外側コイル内に内側コイルを設けた二層構造からなるコイルを用いて、病変部治療を行っているが、特に、石灰化完全閉塞病変部に対する穿孔性能を向上させる為の技術課題が存在する。【解決手段】ガイドワイヤの芯線先端部の先端側を外側コイルに貫挿し、手元側の芯線後端径大部に対する芯線先端部における最小の座屈応力の、芯線の最小座屈応力比を公知特許文献の数倍から数十倍に高めることにより、特に、石灰化完全閉塞病変部での穿孔性能を飛躍的に向上させることができる。【選択図】図1