GROMADA, JESPER,STEVIS, PANAYIOTIS,ALTAREJOS, JUDITH,MURPHY, ANDREW J.
申请号：
CA3094400
公开号：
CA3094400A1
申请日:
2019.04.05
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Provided herein are therapeutic methods of treatment using agonist leptin receptor (LEPR) antibodies, antigen-binding fragments thereof, or compositions comprising the LEPR antibodies or antigen-binding fragments thereof. Such therapeutic methods include treatment for conditions related to metabolic dysfunction, including for example, lipodystrophy, adiposity or obesity, reducing body weight, non-alcoholic fatty liver disease, hyperphagia, hyperglycemia, insulin resistance, dyslipidemia, hepatic steatosis, and infertility.
