Nowe związki pochodne tioflawiny, sposób syntezy związków i  ich zastosowanie, kompozycja farmaceutyczna zawierająca związki i zastosowanie kompozycji

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专利权人:

UNIVERSITY OF PITTSBURGH

发明人:

WILLIAM E. KLUNK,KLUNK WILLIAM E.,CHESTER A.JR. MATHIS,MATHIS CHESTER A.JR.,YANMING WANG,WANG YANMING

申请号：

PL360550

公开号：

PL215711B1

申请日:

2001.08.24

申请国别(地区):

PL

年份:

2014

代理人:

摘要：

This invention relates to novel thioflavin derivatives of the structure useful in, for example, in vivo imaging of patients having neuritic plaques, as well as pharmaceutical compositions comprising the thioflavin derivatives and method for synthesizing the compounds. The compounds find particular use in the diagnosis and treatment of patients having diseases where accum ulation of neuritic plaques are prevalent. The Disease, familial Alzheimers Disease, Downs Syndrome and homozygotes for the apolipoprotein E4 allele.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/