Stable and soluble antibodies that inhibit vegf

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专利权人:

NOVARTIS AG

发明人:

BORRAS, Leonardo,URECH, David,GUNDE, Tea

申请号：

DK17151756

公开号：

DK3216803T3

申请日:

2009.06.25

申请国别(地区):

DK

年份:

2020

代理人:

摘要：

The present invention relates to soluble and stable anti-VEGF imunobinders comprising CDRs from rabbit monoclonal antibodies. Said antibodies are designed for the diagnosis and/or treatment of VEGF-mediated disorders. The hybridomas, nucleic acids, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them and the use of said antibodies in medicine are also disclosed.

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