STABLE AND SOLUBLE ANTIBODIES INHIBITING VEGF

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专利权人:

Novartis AG

发明人:

申请号：

NO2020021

公开号：

NO2020021I1

申请日:

2020.08.04

申请国别(地区):

NO

年份:

2020

代理人:

摘要：

The present invention relates to soluble and stable anti-VEGF imunobinders comprising CDRs from rabbit monoclonal antibodies. Said antibodies are designed for the diagnosis and/or treatment of VEGF-mediated disorders. The hybridomas, nucleic acids, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them and the use of said antibodies in medicine are also disclosed.

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