The present invention relates to the use of a microorganism belonging to the group of lactic acid bacteria or a mutant or derivative thereof, characterized in that it is capable of specifically binding to a bacterium belonging to the group of mutans Streptococci, wherein the specific binding is (i) resistant to heat treatment； and/or (ii) resistant to protease treatment； and/or (iii) calcium-dependent； and/or (iv) formed within a pH range between 4.5 and 8.5； and/or (v) formed in the presence of saliva, for the preparation of an anticariogenic composition for the treatment or prevention of caries caused by mutans Streptococci other than Streptococcus mutans. Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase； (b) mixing said microorganism with a bacterium belonging to the group of mutans Streptococci which has been grown to stationary phase； (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and a bacterium of the group of mutans Streptococci； and (d) detecting aggregates by the occurrence of a pellet. Another aspect of the present invention is a method of prophylaxis or treatment of caries caused by mutans Streptococci other than Streptococcus mutans, comprising administering a microorganism belonging to the group of lactic acid bacteria characterized in that said microorganism is capable of specifically binding to a bacterium belonging to the group of mutans Streptococci or a mutant, derivative, analog or fragment of said microorganism.본 발명은 스트렙토코커스 뮤탄스 이외의 뮤탄스 연쇄상구균에 의해 유발된 우식증의 치료 또는 예방용 항우식성 조성물의 제조를 위한, 뮤탄스 연쇄상구균 군에 속한 세균에 특이적으로 결합할 수 있는 것을 특징으로 하며, 여기서 특이적 결합은 (i) 열 처리에 내성이고/거나； (ii) 프로테아제 처리에 내성이고/거나； (iii) 칼슘-의존적이고/거나； (iv) 4.5 내지 8.5의 pH 범위 내에서 형성되고/거나； (v) 타액의 존재하에 형성되는 것인, 젖산균 군에 속한 미생물 또는 이들의 돌연변이체 또는 유도체의 용도에 관한 것이다. 바람직하게는, 특이적 결합은 아래와 같이 검정될 수 있다: (a) 상기 미생물을 정지기로 성장시키고； (b) 정지기로 성장된 뮤탄스 연쇄상구균 군에 속한 세균과 상기 미생물을 혼합하고； (
