594385 A compound of formula ii-d e.g. N-(5-(4-(3-methyl-2H-pyrazol-5-ylamino)-6-(3-cyclopropyl-3-fluoroazetidin-2-yl)pyrimidin-2-ylthio)pyridin-2-yl)-3,3,3-trifluoropropanamide or a pharmaceutically acceptable salt thereof, wherein the variables are defined in the specification for treating cancer.