1. A combination that includes many polynucleotides that are differentially expressed in animals exhibiting a phenotype, including a decrease in body fat and plasma triglycerides and an increase in saturation, as measured by a decrease in food intake - (RBF / IS phenotype), as a result of prolonged regular intake of the substance, which affects one or more parameters from food absorption, saturation, lipid metabolism and fat utilization, where the polynucleotides are selected from the genes encoding the proteins listed in table 1 or table Its 2, or fragments thereof. ! 2. The combination according to claim 1, in which polynucleotides are selected from genes encoding the proteins listed in group A of table 1 or fragments thereof. ! 3. The combination according to claim 1, in which the polynucleotides are selected from genes encoding the proteins listed in group B of table 1 or fragments thereof. ! 4. The combination according to claim 1, in which polynucleotides are selected from genes encoding the proteins listed in group C of table 1 or fragments thereof. ! 5. The combination according to claim 1, in which polynucleotides are selected from genes encoding proteins involved in β-oxidation of lipids. ! 6. The combination according to claim 1, in which the polynucleotides are selected from genes encoding proteins involved in lipogenesis. ! 7. The combination according to claim 1, in which the polynucleotides are selected from genes encoding proteins involved in lipid transport. ! 8. The combination according to claim 1, in which polynucleotides are selected from genes encoding proteins involved in the transmission of an insulin signal. ! 9. The combination according to claim 1, in which polynucleotides are selected from genes encoding proteins involved in the control of food intake. ! 10. The combination according to claim 1, in which polynucleotides are selected from genes, �1. Комбинация, включающая множество полинуклеотидов, которые дифференцированно экспрессируются