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Immune inducer
专利权人:
オリンパス株式会社;静岡県
发明人:
程 錦雁,丸山 宏二
申请号:
JP2011166051
公开号:
JP5828470B2
申请日:
2011.07.28
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
The purpose is to provide an immunity-inducing agent which can be implanted or injected in vivo by a simple operation and is capable of activating the in vivo immunological actions without causing adverse side effects. An immunity-inducing agent comprising beta-tricalcium phosphate (beta-TCP) having a porosity of 50% or less is implanted or injected in vivo, particularly in the vicinity of a lesion area (non-lesion area) such as cancer. Lymphocytes such as T cells, B cells and NK cells or a dendritic cell can be induced in the vicinity of beta-TCP, and a lymphadenoid tissue is formed in which lymphocytes are localized at a high density. Examples of the dosage form of the immunity-inducing agent include particles or granules having a particle or grain size of equal to or greater than 0.05 mum and less than 25 mum, as well as tablets or columellas.
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