您的位置: 首页 > 农业专利 > 详情页

Hydrophobic acrylic intraocular lens materials
专利权人:
NOVARTIS AG
发明人:
AKINAY, ALI E.,LAREDO, WALTER R.
申请号:
ES12727001
公开号:
ES2538022T3
申请日:
2012.05.31
申请国别(地区):
ES
年份:
2015
代理人:
摘要:
A copolymer ophthalmic device material formed by polymerization of a mixture comprising a) 30-60% (w / w) of an aryl acrylic hydrophobic monomer of formula (I) ** Formula ** wherein: A is H; B is (CH2) m, S (CH2) u, O (CH2) v, or [O (CH2) 2] n; u is 1-4; v is 1-4; C is (CH2) w; m is 1-6; n is 1-10; Y is nothing, O, S or NR, with the proviso that if Y is O, S or NR, then B is (CH2) m; R is H, CH3, CnH2n + 1 (n>; = 1-10), iso-OC3H7, C6H5, or CH2C6H5; w is 0 - 6, with the proviso that m + w - 8; and D is H, C1-C4 alkyl, C1-C4 alkoxy, C6H5, CH2C6H5, Br, F, Cl, or I; b) 0.1-3.9% (w / w) of a macromer of formula (II) ** Formula ** in which R1 and R2 are independently -CH3, -CH2CH3, -CH2CH2CH2CH3, CH2CH2CH2CH3, -C6H5 , -CH2C6H5, - CH2CH2C6H5, -CH2CH2CH2C6H5, or -CH2CH2CH2CH2C6H5; R3 is H, CH3, or CH2CH3; z is 2-11; and x indicates the number of repeating units and determines the molecular weight of the macromer and is such that the macromer has a molecular weight of about 300-3500; c) 10-40% (w / w) of 2-ethylhexyl acrylate or n-octyl acrylate; d) 5-30% (w / w) of a hydrophilic monomer selected from the group consisting of: hydroxy methacrylates (C2-C4 alkyl), glycerol methacrylate, and N-vinyl pyrrolidone; e) a crosslinking monomer; and f) a reactive UV absorber; wherein the material of the copolymer ophthalmic device has an equilibrium water content at 35 ° C of less than 4%.Un material de dispositivo oftálmico copolimérico formado mediante polimerización de una mezcla que comprende a) un 30 - 60 % (p/p) de un monómero hidrófobo aril acrílico de fórmula (I)**Fórmula** en la que: A es H; B es (CH2)m, S(CH2)u, O(CH2)v, o [O(CH2)2]n; u es 1 - 4; v es 1 - 4; C es (CH2)w; m es 1 - 6; n es 1 - 10; Y es nada, O, S o NR, con la condición de que si Y es O, S o NR, entonces B es (CH2)m; R es H, CH3, CnH2n+1 (n >;= 1-10), iso-OC3H7, C6H5, o CH2C6H5; w es 0 - 6, con la condición de que m + w - 8; y D es H, alquilo C1 - C4, alcoxi C1 - C4, C6H5, CH2C6H5, Br, F, Cl, o I; b) un 0,1
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充