THE PRESENT INVENTION AIMS TO PROVIDE A MATRIX-TYPE SOLID PREPARATION THAT HAS HIGH-LEVEL RELEASE CONTROLLABILITY FOR SUPPRESSING DRUG RELEASE IN THE UPPER GASTROINTESTINAL TRACT AND ACCELERATING DRUG RELEASE IN THE LOWER GASTROINTESTINAL TRACT, AND THAT SOLVES OF ALL THE ABOVE DRAWBACKS CAUSED BY COMBINING A PLASTICIZER. THE PRESENT INVENTION PROVIDES A MATRIX-TYPE PHARMACEUTICAL SOLID PREPARATION THAT CONTAINS: (A) A METHACRYLIC ACID-BASED ENTERIC POLYMER AND (B) A SUGAR AND/OR A SUGAR ALCOHOL, WHEREIN 1 G OF THE SUGAR AND/OR THE SUGAR ALCOHOL CAN BE DISSOLVED IN NOT MORE THAN 4 G OF WATER AT A WATER TEMPERATURE OF 20 TO 25°C.
