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Amphiphilic block copolymers for nucleic acid delivery
专利权人:
Andrew Lennard Lewis
发明人:
Andrew Lennard Lewis,Giuseppe Battaglia,Irene Canton,Peter William Stratford
申请号:
US12991321
公开号:
US09254258B2
申请日:
2009.05.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides a composition comprising vesicles and encapsulated within the vesicles, nucleic acid comprising less than 1000 nucleotides, wherein the vesicles comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block.Methods of forming vesicles and methods of delivering nucleic acid, in particular, iRNA into cells, are also provided.
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