PROBLEM TO BE SOLVED: To provide a composition for oral cavity, by using glycyrrhetinic acid to impart anti-inflammatory activity or the like to the composition and improving the stability by successfully dissolving or dispersing the glycyrrhetinic acid, allowing improvement in permeability and adsorptivity to oral cavity mucosa.SOLUTION: A composition for oral cavity comprises the components (A), (B), (C) and (D): (A) 0.014 mass% or more and 0.1 mass% or less of glycyrrhetinic acid or its salt calculated in terms of acid, (B) 0.5 mass% or more and 1.2 mass% or less of polyoxyethylene hardened castor oil, (C) 0.28 mass% or less of N-acyl basic amino acid alkyl ester or its salt, (D) 0.15 mass% or more and 0.5 mass% or less in total of oil components selected from oil flavors, and oil drug effect components except for the component (A), and (E) water. The mass ratio of the content of the component (B) and the content of the component (A) calculated in terms of acid (B/A) is 12 or more and 37 or less, and the mass ratio of the content of the component (C) and the content of the component (A) calculated in terms of acid (C/A) is more than 1 and 20 or less.COPYRIGHT: (C)2014,JPO&INPIT【課題】抗炎症作用等を付与するためにグリチルレチン酸を用いつつ、かかるグリチルレチン酸を良好に溶解又は分散させて安定性を高めながら、口腔内粘膜への浸透性や吸着性の向上をも図ることのできる口腔用組成物を提供する。【解決手段】次の成分(A)、(B)、(C)及び(D):(A)グリチルレチン酸又はその塩 酸換算量で0.014質量%以上0.1質量%以下、(B)ポリオキシエチレン硬化ヒマシ油 0.5質量%以上1.2質量%以下、(C)N-アシル塩基性アミノ酸アルキルエステル又はその塩 0.28質量%以下、(D)油性香料及び成分(A)以外の油性薬効成分から選ばれる油性成分 合計で0.15質量%以上0.5質量%以下 及び(E)水を含有し、成分(B)の含有量と成分(A)の酸換算量での含有量との質量比(B/A)が12以上37以下であって、成分(C)の含有量と成分(A)の酸換算量での含有量との質量比(C/A)が1より大きく20以下である口腔用組成物。【選択図】なし
