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Ring-contracted morphinans and the use thereof
专利权人:
Purdue Pharma L.P.
发明人:
Jeffrey Lockman,Laykea Tafesse
申请号:
US15108091
公开号:
US09656962B2
申请日:
2014.12.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The application is directed to compounds of Formula (I) or (IA) and pharmaceutically acceptable salts and solvates thereof, wherein R1 R2, R3 and G are defined as set forth in the specification. The invention is also directed to use of compounds of Formula (I) or (IA), and the pharmaceutically acceptable salts and solvates thereof, to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.
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