LOCKMAN, Jeffrey,TAFESSE, Laykea,PARK, Jae, Hyun,YOUNGMAN, Mark
申请号：
EP14875495
公开号：
EP3086790A4
申请日:
2014.10.10
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The application is directed to compounds of Formula I or II: and pharmaceutically acceptable salts and solvates thereof, wherein R, R", R" R1, R2, R3, R4, R4a, and R20 are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I or II and the pharmaceutically acceptable salts and solvates thereof to treat disorders responsive to the modulation of one or more opioid receptors. Certain compounds of the invention are especially useful for treating pain.
