DE STAAT DER NEDERLANDEN; VERT. DOOR DE MINISTER VAN VWS
发明人:
VAN DE WATERBEEMD, BAS,VAN DER POL, LEONARDUS ALDOLFUS
申请号：
CA2840096
公开号：
CA2840096A1
申请日:
2012.07.05
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to the fields of medical microbiology and vaccines. In particular the invention relates to a process for detergent-free preparation of outer membrane vesicles (OMV) of Gram negative bacteria for use in vaccines, to OMV obtainable by said process, and to a pharmaceutical composition comprising such OMV. The present invention further relates to the use of OMV of the present invention as a medicament in particular for use in a method for eliciting an immune response.
