VAN DE WATERBEEMD BAS,VAN DER POL LEONARDUS ALDOLFUS
申请号:
IN11085/DELNP/2013
公开号:
IN2013DN11085A
申请日:
2013.12.24
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention relates to the fields of medical microbiology and vaccines. In particular the invention relates to a process for detergent free preparation of outer membrane vesicles (OMV) of Gram negative bacteria for use in vaccines to OMV obtainable by said process and to a pharmaceutical composition comprising such OMV. The present invention further relates to the use of OMV of the present invention as a medicament in particular for use in a method for eliciting an immune response.