GARCIA-MARTINEZ, LEON,JENSEN, ANNE, ELISABETH, CARVALHO,OLSON, KATIE,DUTZAR, BEN,OJALA, ETHAN,LATHAM, JOHN,KOVACEVICH, BRIAN,SMITH, JEFFREY T L
申请号：
NZ58159608
公开号：
NZ581596A
申请日:
2008.05.21
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Provided is an anti-human IL-6 antibody or antibody fragment comprising a variable heavy chain that possesses at least 90% sequence identity to a specified variable heavy chain and/or a variable light chain that possesses at least 90% sequence identity to it or an antibody that having the same epitopic specificity as an antibody or antibody fragment comprising the VH and VL of the specified sequences. Further provided are methods of making the antibody and its use to treat cancers and various other diseases.
