Claim 1: a fully Human anti-cd137 Antibody IgG isolated from a class that binds to an epitope of CD137, wherein Said Antibody comprises a sequence of variable domain of heavy chain that is at least 95% identical in Amino Acid Sequence is selected from the gr Upo is SEQ ID no. 1, SEQ ID no. 3, SEQ ID no. 5, SEQ ID SEQ ID no. 6, no. 7, SEQ ID no. 9SEQ ID no. 11, SEQ ID no. 13, SEQ ID no. 15, SEQ ID no. 17, SEQ ID no. 19, SEQ ID no. 21, SEQ ID no. 23, SEQ ID no. 25, SEQ ID no. 27, SEQ ID no. 29, SEQ ID no. 31, SEQ ID no. 33, SEQ ID no. 35, SEQ ID no. 37, SEQ ID no. 39, SEQ ID no. 41, SEQ ID no. 43, SEQ ID no. 45, SEQ ID no. 47, SEQ ID no. 49 SEQ ID no. 51, SEQ ID no. 53, SEQ ID no. 55 SEQ ID no. 57, SEQ ID no. 59, SEQ ID no. 61 SEQ ID no. 63, SEQ ID no. 65SEQ ID no. 67, SEQ ID no. 69, SEQ ID no. 71, SEQ ID no. 73, SEQ ID no. 75, SEQ ID no. 77, SEQ ID no. 79, SEQ ID no. 81, SEQ ID no. 83, SEQ ID no. 85, SEQ ID no. 87 SEQ ID no. 89, 91 SEQ ID no., SEQ ID no. 93, SEQ ID no. 95, SEQ ID no. 97, SEQ ID no. 99, SEQ ID no. 101, SEQ ID no. 103, SEQ ID no. 1 05, SEQ ID no. 107, SEQ ID no. 109, SEQ ID no. 111, SEQ ID no. 113, SEQ ID no. 115 SEQ ID no. 117, SEQ ID no. 119SEQ ID no. 121, SEQ ID no. 123, SEQ ID no. 125, SEQ ID no. 127, SEQ ID no. 129 SEQ ID no. 130, SEQ ID no. 131, SEQ ID no. 132, SEQ ID no. 133, SEQ ID no. 134, SEQ ID no. 135, SEQ ID no. 136, SEQ ID no. 137, SEQ ID no. 138 SEQ ID no. 139, SEQ ID no. 140, SEQ ID no. 141, SEQ ID no. 142SEQ ID no. 143； and a sequence of light chain variable domain is at least 95% identical at the Amino Acid Sequence is selected from the group consisting of SEQ ID no. 2, SEQ ID no. 4, SEQ ID no. 6, SEQ ID No. 8, SEQ ID no. 10, SEQ ID no. 12, SEQ ID no. 14, SEQ ID no. 16, SEQ ID n No. 18, SEQ ID no. 20, SEQ ID no. 22, SEQ ID no. 24, SEQ ID no. 26, SEQ ID no. 28, SEQ ID no. 30, SEQ ID no. 32SEQ ID no. 34, SEQ ID no. 36, SEQ ID no. 38, SEQ ID no. 40, SEQ ID no. 42, SEQ ID no. 44, SEQ ID no. 46, SEQ ID no. 48, SEQ ID no. 50, SEQ ID no. 52,
