THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL;THE RESEARCH INSTITUTE AT NATIONWIDE CHILDRENS HOSPITAL
发明人:
KASPAR, BRIAN
申请号:
EP13837504
公开号:
EP2895606A4
申请日:
2013.09.17
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The invention relates to pharmaceutical compositions, kits, methods, and uses for the treatment of amyotrophic lateral sclerosis. In particular, the invention relates to pharmaceutical compositions, kits, methods, and uses for the treatment of amyotrophic lateral sclerosis by decreasing the expression of a cytoplasmic granule toxin in astrocytes of a patient, or by increasing the expression of MHC class I in motor neurons of the patient.