A system for hemodialysis can include a first dialysis system and a second dialysis system configured to be used in alternate fashion to provide hemodialysis for a patient, wherein the first dialysis system is configured to be worn by the patient, and wherein the second dialysis system is configured to be positioned on a support independent of the patient. The first dialysis system can be configured to be coupled to a belt worn by the patient around a waist of the patient during its operation. The second dialysis system can configured to be coupled to a stationary support during its operation.