INGEBRITSON, ALAINA,NEUBAUER, AXEL,SMITH, HILDA ELIZABETH,DE GREEFF, ASTRID
申请号：
CA3043039
公开号：
CA3043039A1
申请日:
2017.11.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The invention relates to bacterial infections, vaccines directed against those infections and bacterial vaccines. More particularly, the invention relates to vaccines directed against Streptococcus infections in pigs. Provided is a ?FolT mutant of a bacterium having reduced capacity to transport folate, wherein the capacity has been reduced by functionally deleting folate transporter (FolT) function. Also provided is a method to reduce virulence of a bacterium comprising reducing the capacity of the bacterium to transport folate.
