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Fluorescent polymeric materials containing lipid soluble rhodamine dyes
专利权人:
Joe Y. L. Lam
发明人:
Joe Y. L. Lam,Steven M. Menchen,Ruiming Zou,Scott C. Benson
申请号:
US13026690
公开号:
US08618161B2
申请日:
2011.02.14
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Fluorescent polymeric materials are disclosed comprising a polymeric particle and one or more lipid soluble rhodamine dyes, comprising the following core structure:wherein R11 and R15 are each H or are each F or Cl R12, R13, and R14 are each H or are each F or Cl and wherein at least one of R3′, R3″, R6′ and R6′ is a (C4-C20) alkyl. The materials are especially useful in the preparation of multicolored microparticles, especially multicolored polystyrene microparticle, for use in the multiplexed analysis of a plurality of analytes in a single sample. When excited by a light source, the materials give off a unique emission based on the nature, concentration and ratio of the dyes therein. Methods of preparing and using said materials are also disclosed.
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