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PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS
专利权人:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人:
STRANO, MICHAEL S.,BARONE, PAUL W.,AHN, JIN-HO,YUM, KYUNGSUK,MCNICHOLAS, THOMAS P.
申请号:
CA2843950
公开号:
CA2843950A1
申请日:
2012.07.30
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
A composition for sensing an analyte can include a photoluminescent nanostructure complexed to a sensing polymer, where the sensing polymer includes an organic polymer non-covalently bound to the photoluminescent nanostructure and an analyte-binding protein covalently bound to the organic polymer, and where the analyte- binding protein is capable of selectively binding the analyte, and the analyte-binding protein undergoes a substantial conformational change when binding the analyte. Separately, a composition for sensing an analyte, can include a complex, where the complex includes a photoluminescent nanostructure in an aqueous surfactant dispersion and a boronic acid capable of selectively reacting with an analyte. The compositions can be used in devices and methods for sensing an analyte.
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