PROBLEM TO BE SOLVED: To provide an enhancement method of interleukin 10 production inducing ability of lactic acid bacteria.SOLUTION: An enhancement method of interleukin 10 production inducing ability of a lactic acid bacteria comprises, when culturing, at 37°C for 48 hours, an inoculated bacterial culture obtained by inoculating a bacterial culture into 100% of grape and orange juice at the content of 0.4% respectively, the bacterial culture being obtained by culturing in Lactobacilli MRS Broth culture medium at 37°C for 16 hours until a steady state, culturing a lactic acid bacteria belonging to Lactobacillus plantarum in a culture medium whose pH is adjusted to 2.0-5.7, wherein an achieved viable bacteria count is both 108 CFU/mL or more.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】乳酸菌のインターロイキン10産生誘導能の増強方法の提供。【解決手段】Lactobacilli MRS Broth培地で定常状態になるまで37℃で16時間培養した菌液を、グレープおよびオレンジの100%果汁に対してそれぞれ0.4%容量接種したものを37℃で48時間培養した時の到達生菌数が、共に108CFU/mL以上であるラクトバチルス・プランタラムに属する乳酸菌を、pH2.0~5.7に調整した培地で培養する工程を含む、当該乳酸菌のインターロイキン10産生誘導能の増強方法。【選択図】なし
