PROTEIN KINASE RNA-LIKE ENDOPLASMIC RETICULUM KINASE (PERK) INHIBITORS FOR PREVENTION AND/OR TREATMENT OF LUNG INJURY AND/OR INFLAMMATION

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专利权人:

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

发明人:

Susan S. MARGULIES,Tamas DOLINAY

申请号：

US16096721

公开号：

US20200054638A1

申请日:

2017.04.27

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Disclosed herein are methods of preventing and/or treating lung injury and/or lung inflammation in a subject comprising administering to the subject a therapeutically effective dose of a PERK pathway inhibitor. Pharmaceutical compositions for the prevention and/or treatment of lung injury and/or lung inflammation comprising PERK pathway inhibitors are also provided. Also disclosed are uses of a PERK inhibitor in the manufacture of a medicament for the prevention and/or treatment of a lung injury and/or inflammation.

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http://www.ckcest.cn/home/