PROBLEM TO BE SOLVED: To provide a bone disease improver useful for the prevention or treatment of bone disease.SOLUTION: A bone disease improver has as an active ingredient polysaccharides included in elephant breast milk and having a molecular weight of 80,000-600,000 dalton, the polysaccharides including as constituent sugar at least glucosamine and/or N-acetylglucosamine.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2017,JPO&INPIT【課題】骨疾患の予防又は治療に有効な骨疾患改善剤を提供する。【解決手段】ゾウの母乳中に含まれる分子量8万~60万ダルトンの多糖類であって、構成糖として少なくともグルコサミン及び/又はN-アセチルグルコサミンを含む多糖類を、骨疾患改善剤の有効成分とする。【選択図】図1