Selective inhibitors of clinically important mutants of the EGFR tyrosine kinase

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专利权人:

CS PHARMATECH LIMITED

发明人:

Yuntao Song,Alexander James Bridges

申请号：

US16068559

公开号：

US10435388B2

申请日:

2017.01.06

申请国别(地区):

US

年份:

2019

代理人:

摘要：

The present invention provides compounds of Formula (I) or a subgeneric structure or species thereof or a pharmaceutically acceptable salt, ester, solvate, and/or prodrug thereof and methods and compositions for treating or ameliorating abnormal cell proliferative disorders, such as cancer, wherein A, R2, R3, R10, E1, E2, E3, Y, and Z are as defined herein.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/