SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE

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专利权人:

CS Pharmatech Limited

发明人:

Yuntao SONG,Alexander James BRIDGES,Xiaoqi CHEN

申请号：

US16628831

公开号：

US20200131176A1

申请日:

2018.07.05

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention provides compounds of Formula (I) or a subgeneric structure or species thereof, or a pharmaceutically acceptable salt, ester, solvate, and/or prodrug thereof, and methods and compositions for treating or ameliorating abnormal cell proliferative disorders, such as cancer, wherein A, R2, R3, R10, E1, E2, E3, Y, and Z are as defined herein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/