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Assay for the diagnosis of flaviviral infection using antibodies with high affinity for NS1 protein of flavivirusi in hexameric form
专利权人:
Antoine Talarmin;Sophie Alcon;Vincent Deubel;Marie Flamand;Françoise Megret;Philippe Despres
发明人:
Marie Flamand,Françoise Megret,Sophie Alcon,Antoine Talarmin,Philippe Despres,Vincent Deubel
申请号:
US13190547
公开号:
US08709427B2
申请日:
2011.07.26
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
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