Provided are a photodetector device and a photodetection method as well as a microscope and an endoscope allowing the heterodyne detection of a desired light to be detected with high sensitivity and at a high SN ratio. A photodetector device comprises a local light emitting unit for generating a local light in temporally unstable interference condition with a light to be detected and a photoelectric conversion unit for generating beat signals between the local light and the light to be detected by photoelectric conversion. The light is detected in heterodyne detection based on an output of the photoelectric conversion unit.