The purpose of the present invention is to provide a tableted medicinal composition comprising nalfurafine or a pharmacologically acceptable acid addition salt thereof, said composition having a high moldability and excellent quality control properties of analogous substances. Provided is a tableted medicinal composition comprising nalfurafine or a pharmacologically acceptable acid addition salt thereof, a binder component and a carrier, wherein: the content of nalfurafine or a pharmacologically acceptable acid addition salt thereof is 0.1-10 [mu]g； and the weight of the binder component is 100,000-2,000,000 wt% relative to the weight of nalfurafine or a pharmacologically acceptable acid addition salt thereof and 5-20 wt% relative to the total weight of the obtained medicinal composition, or 20,000-500,000 wt% and 1-5 wt% relative to the total weight of the obtained medicinal composition.本發明之目的係提供一種含有納呋拉啡(nalfurafine)或其藥理學上可容許的酸加成鹽的錠劑化醫藥組成物，其成形性及類似物之品質管理優異。本發明係提供一種錠劑化醫藥組成物，其含有納呋拉啡或其藥理學上可容許的酸加成鹽、結合劑成分、及載體，其中含有0.1~10μg上述納呋拉啡或其藥理學上可容許的酸加成鹽，其中上述結合劑成分之重量係相對於上述納呋拉啡或其藥理學上可容許的酸加成鹽之重量為100,000~2,000,000重量%，且相對於獲得的醫藥組成物之總重量為5~20重量%或20,000~500,000重量%，且相對於獲得的醫藥組成物之總重量為1~5重量%。
