John C. Reed,Xiao-kun Zhang,Bin Guo,Bingzhen Lin,Siva Kumar Kolluri
申请号：
US12364415
公开号：
US08273705B2
申请日:
2009.02.02
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compounds that modulate the function of anti-apoptotic proteins such as Bcl-2 and Bcl-XL are identified. These compounds have the ability to convert the activity of Bcl-2-family member proteins from anti-apoptotic to pro-apoptotic. Methods for inducing apoptosis are described, together with methods for identifying molecules that induce apoptosis through interaction with Bcl-2-family members.
