HARLOW LENE SCHANTZ,PAUL TIMOTHY WARREN,MAYHUGH BRENDAN M,ROBY KELLY ANN,SACHA GREGORY ALLAN,JING XIAONA,HAGARMAN ANDREW,HALBLEIB CALE
申请号：
IN201847029591
公开号：
IN201847029591A
申请日:
2018.08.07
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
Disclosed herein are surfactant free antibody and antibody-drug-conjugate (ADC) formulations for anti-AXL antibodies and ADCs including aqueous formulations lyophilized formulations and reconstituted formulations as well as related processes and uses. The formulations are particularly suitable for an anti-AXL ADC based on an auristatin or DM1 derivative or other similarly hydrophobic drugs. Some formulations comprise histidine and mannitol.
